Blunting The Force Of Disease Is Complicated  COVID-19 vaccines are highly effective at preventing severe disease. But their efficacy in lab-controlled trials may not exactly correlate to how well they work in the real world. David Kaslow, chief scientific officer at the global public health nonprofit PATH, explains that a factor known as the “force of infection” plays a role in determining how well vaccines work. The force of infection describes the attack rate of a pathogen—the amount of time it takes a susceptible individual to get infected in a given population.  In a study recently published in the academic journal NPJ Vaccines, Kaslow and his colleagues found that in vaccine trials for rotavirus and malaria in Africa, efficacy could vary widely between two trial sites. When there were many infections in the community, the overall efficacy of the vaccines appeared lower than in communities where disease incidence was low.  While the same sort of studies haven’t yet been done on the coronavirus outbreak, Kaslow argues that similar factors may be at play now—pointing to a continued need for non-pharmaceutical measures to control transmission, from masking to social distancing.       The Chemistry Of The Perfect Cookie With several major food-related holidays on the horizon, we’ve got a challenge for you—checking your cookie chemistry. Each batch of cookies you make has the potential to be a mini-science experiment, with the specific ingredients you use, the ratios between them, and cooking times and temperatures all variables in the mix.  Jennifer Powers, a science educator at the Oregon Museum of Science and Industry, discusses the role of types of sugar in transforming your cookie’s texture from chewy to crispy. She encourages listeners to take on her educational resource—the Cookie Chemistry Challenge—to engineer the best batch of cookies possible.       Food Failures: Add A Dash Of Science To Your Thanksgiving Recipes This Thanksgiving, put your cooking skills to the test. Looking for tips to avoid singed sweet potatoes, acrid apple pies, and a burned bird? In this archival segment from November 18, 2016, Molly Birnbaum and Dan Souza from Cook’s Science help us understand the science behind favorite Thanksgiving recipes so you can avoid food failures, and get the most out of your roast and side dishes.      America Has A Food Disparity Problem As of 2016, more than half of American children had a diet that standard nutritional recommendations would consider “poor quality.” And there are stark differences between children in wealthier and poorer households. Poor nutrition can have lifelong impacts on health, including Type 2 diabetes, heart problems, and dental cavities. But it isn’t always clear what families need to provide healthier foods for their children. One popular explanation, now debunked, was the theory of food deserts: Poorer neighborhoods just don’t have grocery stores, and families must buy their food from convenience stores and gas stations. But if more grocery stores aren’t the solution, what is?  Sociologist Priya Fielding-Singh explores these questions in a new book, How The Other Half Eats: The Untold Story of Food and Inequality in America. Her research, the product of months of immersive time spent with families in their kitchens and as they navigated grocery stores with kids in tow, describes an alternative explanation for the socioeconomic disparity between kids’ diets. Fielding-Singh explains healthy food takes emotional and energy resources that lower-income parents must often spend in other ways.  Guest host Roxanne Khamsi talks to Fielding-Singh about her research on family food choices, and the kinds of changes that might allow children from all backgrounds to enjoy healthier foods. 

Science Friday

Thanksgiving Food Science, Force of Infection, Food Inequality. Nov 19, 2021, Part 2

Here’s How Biden’s Infrastructure Bill Addresses Science President Joe Biden signed a massive bipartisan infrastructure bill into law this Monday. The measure focuses on a range of sectors. It would funnel billions into cleaning up pollution in the air and water with efforts that include eliminating lead service lines and cleaning up old, polluted manufacturing sites. The bill will also invest $7.5 billion to create a large-scale network of electric vehicle chargers across the country. In other big news this week, a new study confirms that masks are highly effective in combating COVID-19, reducing incidence of the disease by as much as 53% on its own. Researchers say this finding is significant and add that when masks are used in addition to other protective measures, like vaccines and hand washing, people can feel confident in their safety. Joining guest host Roxanne Khamsi to talk through these and other big science stories of the week is Nsikan Akpan, health and science editor for WNYC Public Radio in New York City. Happy (Holiday) Testing Season! The holiday season has snuck up once again, leaving many people to figure out familiar logistics: If travel will be involved, who to see, and what will be for dinner. But of course, we’re still in a pandemic, so questions of safety remain. At the end of the day, we want to keep our families, friends, and loved ones healthy. COVID-19 tests are becoming a popular tool, helping many people make social situations safer. Quickly swabbing your nose or spitting in a tube can indicate if someone has been infected with the coronavirus. But with so many options available, and a big season of holiday get-togethers up ahead, many are wondering what kind of test is best—and when is the best time to get tested? Joining guest host Roxanne Khamsi to talk through COVID-19 testing questions are Dr. Céline Gounder, epidemiologist and professor at New York University’s Grossman School of Medicine in New York, and Dr. Alex Greninger, assistant director at the clinical virology laboratories at the University of Washington Medical Center in Seattle. The Big Bang Theory Of Cancer Despite tremendous scientific advances, there’s still so much scientists don’t understand about cancer. One of the biggest remaining questions is how do tumors form in the first place? Researchers are getting closer to an answer. For years, the prevailing theory of tumor growth was that cancer cells gradually acquire a series of mutations that enable them to outcompete healthy cells and run amok. But improved genetic sequencing of cancers is revealing a more complicated picture. New technology has enabled a new theory of tumor development, called the big bang theory. It turns out that some types of cancer contain a whole hodge-podge of mutations right from the very beginning, even before the tumors are detectable on a scan. Researchers initially observed this pattern in colon cancer, and then replicated the findings in pancreatic, liver, and stomach cancers, too. Guest host Roxanne Khamsi talks to Christina Curtis, associate professor of medicine and genetics at Stanford University’s School of Medicine about her research into tumor development, and how to improve cancer diagnosis and treatment.

Picking Right COVID Test For Holidays, “Big Bang Theory” Of Cancer. Nov 19, 2021, Part 1

As Wildfire Intensity Rises, So Does The Human Toll Of Blazes It was Labor Day 2020, and Mammoth Pool Reservoir, in California’s Sierra Nevada, was buzzing with campers. Karla Carcamo and her parents, siblings, cousins, and countless others, mostly from the Los Angeles area, have been coming here every Labor Day for 17 years. “Most of it is my family, and family that’s invited family, and those family friends have invited friends of theirs,” she says. “I’m telling you, we have over 200 people.” Alex Tettamanti and her husband Raul Reyes are also Labor Day regulars. Every year, they drive in from Las Vegas to meet up with an off-roading club made up of a few dozen families from across the West. They fill their weekend with jet-skiing, ATVing and hiking. “It’s beautiful,” says Tettamanti. “The smell of all the pine trees and stuff, and the trees are so big, it’s really cool. The campground and reservoir are nestled at an elevation of about 3,000 feet in the Central California foothills a few hours northeast of Fresno. The attraction is unfiltered Sierra Nevada: Sparkling blue water surrounded by a thick forest of stately ponderosa pines and black oaks. Plus, it’s isolated. There’s only one road in and out, which dead ends at the lake. “Being there, let me tell you, it’s like a little piece of paradise,” says Carcamo. That Friday passed like any other. Groups split up to go hiking, swimming and grilling, and Carcamo’s family prepared for their annual pupusa night later in the weekend. By Saturday morning, however, the atmosphere had changed. “When I woke up, I did notice it was kind of cloudy,” says Reyes. “The sky was orange and there was ash, like big pieces of ash falling,” says Reyes’ friend Vicky Castro. Read the rest at sciencefriday.com.   Squirrel-Nut Economics And Other Agility Tricks In many parts of the country, the lead-up to winter is a busy time for squirrels, furiously collecting and hiding acorns and nuts for the cold months ahead. But how can squirrels recall where it has stashed all its stores? And what can studying squirrels tell researchers about memory, learning, and economic decision-making in other species? Ira talks with Lucia Jacobs, a professor in the department of psychology and the Institute of Neuroscience at UC Berkeley, about her studies of the campus squirrels—from learning about their cognition, learning, and memory to recording the acrobatic movements of a squirrel on the ground and in the treetops. Jacobs co-leads a "squirrel school," observing rescued and orphaned juvenile squirrels as they learn normal squirrel behavior, and is contributing to a project seeking to develop robots using agility tricks learned from the rodents.   What Will We Reap Without Topsoil? You may have missed the research when it came out this February: a paper in the Proceedings of the National Academies of Science reporting on satellite studies of farmland topsoil in the nation’s corn belt, states like Iowa, Indiana, and Illinois. And the news was not good. The team estimated that more than one-third of the topsoil in this region is gone, eroded mostly from hilltops and ridgelines, thanks to the plowing and tilling processes used to perform industrial agriculture. That topsoil, some of the richest in the world, is carbon-rich and crucial to our food supply. And yet it’s continuing to wash away, a hundred years after scientists like Aldo Leopold first called out the threat of erosion. This erosion, as well as other degradation of soil’s complex structure and microbiome, continues at a fast clip around the globe, hurting food production and ecosystems health. In addition, soil could be helping us contain more than 100 billion additional tons of carbon dioxide from the atmosphere—if we let it. But the good news, according to University of Wisconsin soil scientist Jo Handelsman, is that the solutions like cover crops and no-till farming are simple, well-understood, and easy to implement—as long as we give farmers incentives to make the leap. She talks to Ira about her forthcoming book, A World Without Soil: The Past, Present, and Precarious Future of the Earth Beneath Our Feet.

Mammoth Pool Fire, Fun Squirrel Facts, Soil Importance. Nov 12 2021, Part 2

Psilocybin Effective In Treating Serious Depression Depression is often treatable with medication, therapy, or a combination of the two. But some 30% of patients don’t respond well to existing medications—and may try multiple antidepressant drugs with little or no improvement. This week, researchers reported that a new trial suggests psychedelics may be an effective therapy for treatment-resistant depression. A randomized, controlled, double-blind trial found that people with treatment-resistant depression who were given 25 milligrams of psilocybin, the psychedelic component of magic mushrooms, had a significant decrease in depressive symptoms. The treatment didn’t work for everyone, however, and more research needs to be done before the finding can move to clinical use. Sabrina Imber, a science fellow at the New York Times, joins Ira to talk about the trial and other stories from the week in science—including a new timeline for the planned Artemis missions to the moon, screaming bees, and a very wayward eagle. Activists And Vulnerable Nations At COP26 Seek More Than Promises There’s a big international climate summit wrapping up in Glasgow, Scotland this week. COP26 is the followup to 25 previous United Nations meetings about how the world must respond to the climate crisis—and its shortcomings in doing so. This year leaders had a big conversation to tackle: Countries needed to pledge to reduce emissions even further to prevent a global temperature rise of more than 1.5 degrees Celsius. To do so, they needed to finish hashing out the details of how they will enforce the 2015 Paris Agreement’s provisions. Meanwhile, island nations and other vulnerable countries, who themselves don’t emit much carbon, have continued to lobby for payment for what’s called loss and damages. That’s the harm they’ve already encountered as seas rise, threatening to obliterate their existence. The first week kicked off with bold pledges about methane emissions, coal phaseouts, and ending deforestation. This week, former President Obama spoke about the need for urgent action, and called out large greenhouse gas polluters like Russia and China for not attending. And a grim United Nations report was released, forecasting that despite all the bold pledges, the world was on track to warm a dangerous 2.4 degrees Celsius. The team of Threshold, a podcast that tells stories about our changing environment, has been reporting on these updates from Glasgow, talking to attendees and occasionally witnessing negotiations. In today’s show, Ira talks to journalist Amy Martin, Threshold’s executive producer and host, about her opinion on the outcome of COP26—and if transformative change can still come out of this year’s meeting.   ”Dopesick” Takes On The Opioid Crisis The opioid epidemic has affected millions of people across the country—and more than 800,000 people are estimated to have died from an opioid overdose. At the root of this crisis is the painkiller Oxycontin, manufactured by Purdue Pharma. The company has made billions of dollars from the drug; but has also spent the better part of the last two decades fighting legal battles over its impacts, falsely arguing the drug is non-addictive and completely safe. Meanwhile, people from all walks of life, particularly in small towns across America, have been crippled by addiction to Oxycontin. The limited series “Dopesick” traces the story of the opioid epidemic, from the creation of the Oxycontin pill to a landmark legal battle where Purdue Pharma admitted it misbranded the drug as being less addictive than other prescription opioids. “Dopesick” follows a wide range of characters, from Purdue Pharma executives and federal prosecutors, to an Appalachian doctor and his pain-addled patients. Joining Ira to talk about bringing the show and its people to life is Danny Strong, creator and writer of “Dopesick,” joining from New York, New York.

Psychedelics Can Treat Depression, Climate Meeting, Dopesick Show. Nov 12 2021, Part 1

Fact Check My Feed: More Kids Can Get COVID-19 Vaccines. Now What? Many parents around the U.S. breathed a sigh of relief—or an even more intense emotional reaction—at the long-awaited news that the Centers for Disease Control and Prevention (CDC) had signed off on advising the Pfizer-BioNTech COVID-19 vaccine for children aged 5 to 11 this week. The recommendation came after a unanimous vote from the agency’s committee of outside vaccine experts. And last week, the Food and Drug Administration (FDA) authorized the shot after a review of clinical trial data found both low risk and high efficacy in a smaller, kid-calibrated dose of the vaccine. University of Saskatchewan virologist Angela Rasmussen joins Ira to look at the data behind the FDA’s long-anticipated decision. They also discuss the rationale behind booster shots for high-risk adults, what it means that deer in Iowa have been caught transmitting the virus, COVID-pragmatic holiday planning, and other pandemic news.   In First Real-World Experiment, Red Seaweed Cuts Methane In Cows By More Than Half Methane emissions are a hot topic—largely because it’s a big contributor to climate change. Methane makes up about 10% of human-caused greenhouse gas emissions. 27% of that comes from the burps of ruminant animals, such as cows. In April, Science Friday did a story about research that showed promising results when steers were fed small amounts of the red algae Asparagopsis in their diets. At the time, these experiments were only done in a closely controlled university setting. Now, the first real-world study on a working dairy farm has been completed. The results? Methane released by the seaweed-eating cows was 52% less on average than their non-seaweed-munching counterparts. Coming on the heels of the Biden administration’s methane emissions reduction plan, SciFri producer Kathleen Davis sits down with three key players in this milestone: Joan Salwen, CEO of Blue Ocean Barns in Kailua-Kona, Hawaii, the company that produces the Asparagopsis seaweed powder; Dr. Breanna Roque, animal science consultant at Blue Ocean Barns in Townsville, Queensland, Australia; and Albert Straus, founder and CEO of Straus Family Creamery in Marshall, California.   The Science Friday Theme Song That Got Lost In The Mail Back in 1998, comedian and author Steve Allen, first host of The Tonight Show, joined Ira on Science Friday to talk about the importance of critical thinking. Allen had written a book called Dumbth, calling for improvements in the public’s logical reasoning abilities. Ira was a longtime fan of Allen’s, and eagerly invited him to discuss the book. During the interview, Allen also took to the studio piano to play his signature song, “This Could Be The Start of Something Big.” As the comedian was leaving, Ira jokingly remarked that Science Friday could use a theme song of its own. Several years later, while cleaning the cluttered SciFri office, staff uncovered an unopened box of mail—including an envelope from Hollywood containing a single cassette tape, marked “Theme Song For Science Friday—Steve Allen.” As part of Science Friday’s 30th anniversary celebrations, Ira and SciFri director Charles Bergquist recount the story of the tape, and finally premiere the song, written and performed by the late Steve Allen.      

Kids Under 12 Vaccine, Reduced Cow Methane From Seaweed Diet, Lost SciFri Theme Song. November 5, 2021, Part 2

Behind The FDA’s Decision To Vaccinate Kids Under 12 This week, Pfizer’s COVID-19 vaccine for kids under 12 was officially recommended by the CDC, after a unanimous vote from its independent advisory committee and the FDA’s authorization based on safety and efficacy data. In their analysis, the FDA said the benefits of the vaccine “clearly outweigh” the risks. The risks, which were referenced in a cost-benefit examination of the data, included circumstances that popped up in the study that were unrelated to getting the vaccine (like a broken arm and an accidentally swallowed penny that occurred during the observational period). As parents around the U.S. race to find appointments, Ira talks to science journalist Maggie Koerth about the safety data and what’s next for parents of young kids, including those under 5. They also discuss a NASA test of a system to defend the planet from killer asteroids, a new prediction that climate change will change the availability of food crops within the next ten years, and other science news headlines.   What’s Next For Kansas After 20 Years Of Wind Power? The wind farm business in Kansas has hit its awkward adolescence. It’s still growing 20 years in, but unsure what the near future might hold. If it wants to get through those tough years and continue to grow, it needs to find more workers, to figure out what to do with the dated-but-not-obsolete turbines erected two decades ago and to sort out a way to carry all that wind-harvesting muscle beyond the state’s borders. Consider the burly, newest version of wind farming at the Cimarron Bend wind farm south of Dodge City. “We just watch and listen to the towers,” said project supervisor Dewain Pfaff, who’s responsible for keeping about 300 turbines up and running. “If you can hear a noise we want to mitigate those issues as soon as possible.” Standing at the base of one of the newest turbines on the site, he’s dwarfed by the tower that rises 300 feet into the air. That’s almost as tall as the Kansas State Capitol. Add in the blade when pointing straight up and it’s taller than the tallest building in the state. That mammoth size is one way wind turbines have changed over the past 20 years. While the turbine is nearly 300 feet tall, the turbines at the very first large-scale wind farm in the state stretched only 200 feet above the ground. Transporting larger towers and blades is trickier, but inevitable. Read the rest at sciencefriday.com.   SciFri Reflects On Three Decades Of Covering Science News Thirty years ago this week, on Nov 8, 1991, the first episode of Science Friday aired as part of NPR’s “Talk of the Nation” series. After 30 years, over 9,000 interviews, and several changes of distributors, offices, and studios, the program is still going strong. In this segment, host and executive producer Ira Flatow and SciFri director Charles Bergquist reminisce about some of the great guests and listener questions they’ve heard over the course of the program—from the very first episode, featuring the late Nobel Laureate Sherwood Rowland talking about the ozone hole, to a young fan helping to celebrate SciFri’s Cephalopod Week with her own ode to an octopus. Plus, moments with Jane Goodall, Sylvia Earle, astronaut Leland Melvin, the late Carl Sagan, and more.

30 Years Of Science Friday, Kansas’ Wind Energy Plan, Vaccinating Kids Under 12. November 5, 2021, Part 1

Younger Kids Next In Line For COVID-19 Vaccines This week, an FDA advisory panel voted unanimously to recommend that the COVID-19 vaccine made by Pfizer vaccine be approved for children as young as 5. If the FDA concurs and the CDC agrees, lower-dose Pfizer vaccinations could soon be available for children ages 5 to 11, via local pediatricians. Just who will be immediately eligible for the doses, and how vaccinating young children might affect school mask policies and other restrictions, remains to be seen. Umair Irfan, staff writer at Vox, joins Sophie Bushwick to talk about the news and other stories from the week in science, including potential COVID-related criminal charges against Brazil’s Jair Bolsonaro, an experimental bionic vision implant, and the possible discovery of an exoplanet in the galaxy Messier 51.   Could Ordinary Household Objects Be Used To Spy On You? In the movies, if a room is bugged, the microphone might be hidden in a potted plant. But in recent years, researchers have come up with ways to use the trembling leaves of a potted plant, light glancing off a potato chip bag, and even tiny jiggles in the head of a spinning hard drive caused by a nearby conversation to be able to listen to what’s happening in a room, or to gain information about what’s going on nearby. On a larger scale, other researchers have been able to use the vibrations of an entire building to paint a picture of movements within it—and even the health status of the people inside. The approach is known as a side-channel attack: Rather than observing something directly, you’re extracting information from something else that has a relationship with the target. Many of the approaches are not straightforward—they require an understanding of the physics involved, and sometimes heavy data-processing or machine learning to interpret the hazy information yielded by these techniques. Jon Callas of the Electronic Frontier Foundation, Hae Young Noh of Stanford, and Kevin Fu of the University of Michigan join host Sophie Bushwick to talk about the risks and opportunities afforded by these sneaky methods of surveillance, and how concerned you should be.   A Maggot Revolution In Modern Medicine In a bloody battle during World War I, two wounded soldiers were stranded on the battlefield in France, hidden and overlooked under some brush. Suffering femur fractures and flesh wounds around their scrotum and abdomen, they lay abandoned without water, food, or shelter for a whole week. At the time, outcomes for these kinds of wounds were poor: Patients with compound femur fractures had a 75 to 80% mortality rate. By the time the soldiers were rescued and brought to a hospital base, orthopedic surgeon William Baer expected their wounds to be festering, and their conditions fatal. But much to his surprise, neither showed any signs of fever, septicaemia, or blood poisoning. When his team removed the soldiers’ clothing, they discovered that their flesh wounds were filled with thousands of maggots, or baby flies—little larvae with a massive appetite for decaying matter. Baer was repulsed by the sight, and the team quickly washed off the wriggling maggots. Underneath, instead of the expected pus and bacteria-infected flesh, Baer marveled over “the most remarkable picture.” “These wounds were filled with the most beautiful pink granulation tissue that one could imagine,” Baer later wrote in a 1931 report in the Journal of Bone and Joint Surgery. Maggots have long been associated with death, but in this case, they were helping the soldiers stay alive. As these insects were simply tucking in for their typical meal of dead, decaying flesh, they were inadvertently aiding the soldiers by cleaning their wounds, keeping infection at bay. The soldiers recovered—saved by their tiny, wriggling “friends which had been doing such noble work,” Baer wrote. Baer’s paper is one of the first reports of maggots used in medicine, but these insects have been found healing wounds for thousands of years, with references in the Old Testament and in ancient cultures of New South Wales and Northern Myanmar. Read the rest on sciencefriday.com.

Kids Next For Pfizer Vaccine, Side-Channel Surveillance, Medical Maggots. Oct 29, 2021, Part 1

The Science Behind Cryptid Sightings People around the world have long been fascinated by the idea that there are strange creatures out there, ones that may or may not exist. Tales circulate about cryptids–animals whose existence can’t be proved—like Bigfoot hiding out in American forests, or sea serpents lurking just below the water in coastal towns. Despite the best efforts of monster hunting T.V. shows and amateur sleuths, there may never be concrete proof that these creatures exist. But that doesn’t stop people from analyzing strange photographs or odd carcasses and saying maybe, just maybe, cryptids do exist. Darren Naish, a paleontologist and author based in Southampton, U.K., has a particular interest in looking at cryptozoology—from a skeptical perspective. His breakdowns of cryptid sightings from a scientific perspective have been published in Scientific American, his website, and in his book, Hunting Monsters: Cryptozoology and the Reality Behind the Myths. Darren speaks to guest host Sophie Bushwick about faked evidence, his relationship with cryptozoology, and how cryptids may lead to other pseudoscience beliefs.   Stories From Those On The Frontlines Of Sea Level Rise Next week marks the start of the UN’s annual conference on climate change in Glasgow, Scotland. It’s a big moment for global consensus on climate change: Nations are supposed to make new, aggressive pledges to lower their emissions in the attempt to prevent the planet from hitting 1.5 degrees Celsius of warming. Meanwhile, in the world we see and touch, seas are already rising. In some coastal areas, seas have risen between 0.5 to 1.5 feet in the last century. We’re also already seeing hurricanes with higher storm surge, and heavier rainfall. More change, of course, is projected. The SciFri Book Club has been talking about these risks, and reading about how these numbers have endangered wetlands, flooded homes, lost livelihoods, and sometimes scattered communities in Elizabeth Rush’s 2018 book Rising: Dispatches From The New American Shore. But while we’ve talked to wetland scientists and Elizabeth herself, the voices of community members most affected by climate change—a key part of Rising’s mission—were still missing. In a final conversation with guest host Sophie Bushwick, producer Christie Taylor shares some of the stories of people on the frontlines, including a real-estate agent who helped his neighbors relocate after Hurricane Sandy, and the leader of the Gullah Geechee people on the sea islands of the southeast coast. Plus, social scientist A.R. Siders’ insights into communities’ need to adapt to sea level rise, and how they can be most successful.   Listen To The Haunting Howls That Once Permeated Europe Last year, Melissa Pons, a field recordist and sound designer, set out to capture a sound that at one time would have been familiar to almost any European: the howl of an Iberian wolf. There was a time when the sounds of wolves filled the forests and mountains of Europe. But after centuries of persecution by humans, only some 12,000 wolves remain in all of Europe. Isolated pockets of wolves can be found in Italy, Spain, Greece, and Finland. A sixth of the entire remaining population lives in the mountains of Portugal. Pons headed to the remote, mountainous region of Picão—a settlement on the small island Príncipe off the west coast of Africa—where there is a rehabilitation center for the Iberian wolf. There are some 350 packs of wolves spread out over about 45 acres of the reserve. Pons first explored the region and observed the wolves. Then she set up her recording gear and gathered over 100 hours of tape. From those recordings, she composed an album where each track captures a distinct soundscape made by these wolves. The album is available online and half the proceeds go toward supporting the rehabilitation center in Portugal.  

Rising Seas Stories, Pseudo-Biology of Monsters, Howling Wolf Soundscape. Oct 29, 2021, Part 2

The Ancient Neanderthal Traces Hidden In Your Genome Just how much of your genome is uniquely human? It turns out the number of genetic components in the human genome that trace back only to modern humans, and not to other human lineages or ancient ancestors, are surprisingly small. In a paper published recently in the journal Science Advances, researchers estimate the uniquely human portion of the genome as being under two percent.  Many of the genes thought to be strictly connected to modern humans appear to relate to neural processes. However, traces of genes from Denisovans and Neanderthals can be found scattered throughout the genome—including strong Neanderthal genetic signals in parts of the genome dealing with the immune system.Ed Green, a professor of biomolecular engineering at the University of California Santa Cruz and one of the authors of that paper, joins SciFri’s Charles Bergquist to talk about the study, and what can be learned by this approach to studying our genetic code.     Beavers Build Ecosystems Of Resilience Deep in the Cameron Peak burn scar, nestled among charred hills, there’s an oasis of green—an idyllic patch of trickling streams that wind through a lush grass field. Apart from a few scorched branches on the periphery, it’s hard to tell that this particular spot was in the middle of Colorado’s largest-ever wildfire just a year ago. This wetland was spared thanks to the work of beavers. The mammals, quite famously, dam up streams to make ponds and a sprawling network of channels. Beavers are clumsy on land, but talented swimmers; so the web of pools and canals lets them find safety anywhere within the meadow. On a recent visit to that patch of preserved land in Poudre Canyon, ecohydrologist Emily Fairfax emphasized the size of the beavers’ canal network. “Oh my gosh, I can’t even count them,” she said. “It’s a lot. There’s at least 10 ponds up here that are large enough to see in satellite images. And then between all those ponds is just an absolute spiderweb of canals, many of which are too small for me to see until I’m here on the ground.” The very infrastructure that gives beavers safety from predators also helps shield them from wildfire. Their work saturates the ground, creating an abnormally wet patch in the middle of an otherwise dry area. Dams allow the water to pool, and the channels spread it out over a wide swath of valley floor. Fairfax researches how beavers re-shape the landscapes where they live. Across the West, she’s seen beaver-created wetlands survive wildfires. Ira chats with Fairfax and KUNC's Water in the West reporter Alex Hager about how beavers are creating wetland oases that are surviving the West's new megafires.       DIY Halloween Hacks Trying to liven up your ghosts and goblins this Halloween? In this archival segment from 2013, Windell Oskay, cofounder of Evil Mad Scientist, shares homemade hack ideas for a festive fright fest, from LED jack-o’-lanterns, to 3D printed candy, to spine-chilling specimen jars.      The Burn Of Volcanic Beauty This week, Mount Aso, a volcano in Japan, erupted—spewing clouds of ash and smoke, but fortunately bringing no reported injuries. Meanwhile, on the island of La Palma, the Cumbre Vieja volcano has been erupting for over a month now, causing destruction and evacuations on the island, and dramatically changing the island’s coastline.  Robin George Andrews, author of the upcoming book Super Volcanoes, joins Ira to talk about the terror—and wonder—of volcanoes, and why their behavior can be so enigmatic to humans.   

Genome Traces, Beavers and Wildfire, Halloween DIY, Volcanoes. Oct 22, 2021, Part 2

Biden’s Administration Preps For A Crucial Climate Conference This week, CDC advisers gave their support to approve COVID-19 vaccine boosters for those who received Moderna and J&J vaccines. The recommendations would follow the U.S. Food and Drug Administration’s authorization of “mixing and matching” booster shots from different vaccine developers. Ira provides new updates on the latest vaccine booster approvals, and a story about a successful transplant of a pig kidney… to a human. Plus, climate reporter Kendra Pierre-Louis gives us a closer look at how the United States is living up to its Paris Agreement pledges as a crucial international gathering looms, and Biden’s clean energy legislation appears to be faltering.      Seeing The History Of Filipinos In Nursing You may have seen a grim statistic earlier this year: 32% of U.S. registered nurses who died of COVID-19 by September 2020 were of Filipino descent, even though they only make up 4% of nurses in the United States. Yet an event like the pandemic is disproportionately likely to affect Filipino-American families: Approximately a quarter of working Filipino-Americans are frontline healthcare workers. There’s a deep history of Filipino immigrants and their descendants in frontline healthcare work. This Filipino-American History Month, Ira talks to nurse and photojournalist Rosem Morton and freelance journalist Fruhlein Econar about their recent collaboration for CNN Digital, using photographs from Morton’s “Diaspora on the Frontlines” project.  They talk about the long reliance of the U.S. healthcare system on the Philippines, and the importance of documenting the lives, not just the disproportionate hardship, of these frontline healthcare workers and their families.       Francis Collins, Longest-Running NIH Director, To Step Down Francis Collins, director of the National Institutes of Health (NIH), will be stepping down from his post at the end of the year. Collins is the longest serving NIH director, serving three presidents over 12 years: Barack Obama, Donald Trump, and Joe Biden. Before his role at the NIH, Collins was an acclaimed geneticist, helping discover the gene that causes cystic fibrosis. He then became director of the National Human Genome Research Institute, where he led the project that mapped the human genome.  A lot can happen in 12 years, especially in the fields of health and science. Collins joins Ira to talk about his long tenure at the NIH, as well as how his Christian faith has informed his career in science. 

Filipino Nurses, Francis Collins Exit Interview. Oct 22, 2021, Part 1

On Long Island, A Tribal Nation Faces Growing Pressures The Hamptons on Long Island are known as a mansion-lined escape for wealthy New Yorkers. But the area is also home to the Native residents of the Shinnecock Tribal Nation. An estimated 1,500 Shinnecock members are left in the U.S., and about half live on the Nation’s territory on Long Island. As with the rest of the island, Shinnecock Nation is extremely vulnerable to climate change. Receding shorelines threaten to eat up three-quarters of its territory by 2050, adding to the existing threat of development from the Hamptons. This issue of climate change and its impacts around Long Island is the subject of the new podcast, “Higher Ground,” from WSHU Public Radio in Fairfield, Connecticut. One of the stories told in the podcast is that of Tela Troge, Shinnecock tribal sovereignty attorney and kelp farmer, who lives on Shinnecock territory in Long Island.  Tela talks to Ira about seeing climate change and development affect Shinnecock land with her own eyes, and her venture into kelp farming as a tool for nitrogen sequestration.      The World According To Sound: Listening To Lightning There is more than one way to listen to a bolt of lightning. While you can pick up the boom and rumble of thunder with your ears, if you tune in with a radio receiver, you can hear an entirely different sound: an earth whistler. When lightning strikes, it releases electromagnetic radiation in the VLF or Very Low Frequency band, which runs from 3 Hz to 30 kHz. This falls within the human range of hearing, which spans from 20 Hz to 20 kHz. However, we can not hear whistlers with our own ears because the radiation is electromagnetic, not physical vibrations in the air. We can, though, capture the electromagnetic radiation with a radio receiver. Radio operators have been picking up the strange twanging of lightning ever since they started trying to tune into man-made signals. They dubbed the eerie electro-magnetic disturbances in their headphones “earth whistlers.” People first heard earth whistlers back in the 19th century. The electromagnetic radiation from lightning interfered with telephone lines and crept into phone conversations. You’d be talking with someone and hear these bursts of energy, like little phone ghosts.  Today, we know earth whistlers are made by the interaction of lightning with the planet’s magnetic field. There are over a million lightning strikes in the atmosphere, which means there is a nearly constant chorus around earth.  The whistlers in this piece were provided courtesy of NASA and The University of Iowa.  The World According to Sound is a live audio show, online listening series, and miniature podcast that focuses on sound, not story. Producers Chris Hoff and Sam Harnett create intentional, communal listening experiences as a way to “reclaim autonomy in a visually dominated world that is increasingly fracturing our attention.”  This recording is part of their next listening series, an immersive listening party where audiences from all over the globe will be invited to experience a world of sound together, beginning in January 2022. You can get a ticket to the series here.      Save The Wetlands, Save The World In Rising, the Science Friday Book Club pick for this fall, author Elizabeth Rush writes frequently of marshes. Rush explores the disappearing wetlands of Louisiana’s hurricane-battered coast, the San Francisco Bay Estuary, Staten Island’s newly abandoned flood zones, and other marshes around the country. But why, scientifically speaking, are wetlands such a feature of the conversation around coastal resilience to climate change and rising seas.  In a recording with a ‘live’ Zoom audience, SciFri producer Christie Taylor speaks with wetland ecologists Marcelo Ardón and Letitia Grenier about the resilience and adaptability of marshland, how climate change and sea level rise threatens them, and why protecting and restoring tidelands is good for everyone.      Widening The Lens On A More Inclusive Science In 2012, the Obama administration projected that the United States would need to add an additional 1 million college graduates in STEM fields per year for the next ten years to keep up with projected growth in the need for science and technology expertise. At the same time, though, native Americans and other Indigenous groups are underrepresented in the sciences, making up only 0.2% of the STEM workforce in 2014, despite being 2% of the total population of the United States. Why are Indigenous people still underrepresented in science?   In this re-broadcast of the 2019 conversation, Ira speaks with astrophysicist Annette Lee and anthropologist Kim TallBear about the historical role of science and observation in Indigenous communities, and how Western scientific culture can leave out other voices. They also discuss the solutions: What does an inclusive scientific enterprise look like, and how could we get there?      This Weekend, Take Time For The Moon This Saturday marks International Observe the Moon Night, a worldwide astronomy education event encouraging people to take time to look at the moon—through a telescope, if possible. Around the world, astronomers will be setting up public telescopes and encouraging passers-by to take a look.  Dean Regas, astronomer at the Cincinnati Observatory, joins Ira to explain how to get in on the lunar-observation action. They also talk about other astronomical events, including the ongoing Orionid meteor shower and an upcoming partial lunar eclipse on November 19.  

Shinnecock Nation, Marsh Science, Weekend Stargazing. Oct 15, 2021, Part 2

More Boosters, For More People This week, an FDA advisory committee met to pore over data and debate the role of COVID vaccine boosters. And on Thursday, they voted to recommend Moderna boosters for older Americans, as well as people in certain at-risk groups. This recommendation came just a few weeks after the FDA authorized a Pfizer booster for similar individuals. The recommendations of the panel regarding boosters for Moderna and Johnson & Johnson vaccines, as well as the idea of mixing and matching different vaccine and booster types, will now go to FDA officials. The CDC will also weigh in. Amy Nordrum, commissioning editor at MIT Technology Review, joins Ira to talk about the vaccine meeting and other topics from the week in science—including the FDA authorization of an e-cigarette, efforts to map the brain, mysterious radio signals from space, and a mission to explore asteroids near Jupiter.   Indigenous-Led Biology, Designed For Native Communities Monday was Indigenous Peoples’ Day here in the United States: a holiday to honor Native Americans and their resilience over many centuries of colonialism. Due to a long history of discrimination, Native Americans face stark health disparities, compared to other American populations. Illnesses like chronic liver disease, diabetes, and respiratory diseases are much more common in Native communities. This is where the Native BioData Consortium (NBDC) comes in. It’s a biobank, a large collection of biological samples for research purposes. What sets this facility apart from others is its purpose—the biological samples are from indigenous people, and the research is led by indigenous scientists. This is important, say the founders, because for too long, biological samples from Native people have been used for purposes that don’t benefit them. Joining Ira to talk about the importance of having a biobank run by indigenous scientists are three foundational members of the project: Krystal Tsosie, co-founder and ethics and policy director of the NBDC and PhD candidate in genetics at Vanderbilt University, Joseph Yracheta, executive director and laboratory manager of the NCDC, and Matt Anderson, assistant professor of microbiology at Ohio State University and NCDC board member.   Indigenous Activists Helped Save Almost A Billion Tons Of Carbon Per Year This summer, Science Friday and other media outlets covered the protests against an oil pipeline project in northern Minnesota, where Canadian company Enbridge Energy was replacing and expanding their existing Line 3 infrastructure. Native American tribes in Minnesota—whose lands the pipeline would pass through and alongside—organized protests, direct action, and other resistance against the project. The pipeline was completed, and began moving tar sands oil at the beginning of October. But the protests and their non-Native allies drew arrests, news coverage, and social media attention to the debate over continued drilling of fossil fuels. Before Line 3, there were protests at the Dakota Access Pipeline, which was completed against the wishes of the nearby Standing Rock Sioux Tribe, and the Keystone XL pipeline, which President Biden ultimately cancelled after objections and lawsuits from two Native American communities in Montana and South Dakota. So far, the Arctic National Wildlife Refuge has remained un-drilled, despite multiple attempts, with help from vocal opposition by Alaska’s Gwich’in people. A new report from two advocacy groups does the math on how much carbon dioxide or other greenhouse gas emissions these cancelled or delayed projects would have emitted in the last 10 years. According to their calculations, Indigenous resistance to pipelines and other fossil fuel projects has saved the U.S. and Canada 12% of their annual emissions, or 0.8 billion tons of CO2 per year. Ira talks to the co-authors, Dallas Goldtooth of the Indigenous Environmental Network, and Kyle Gracey from Oil Change International, about the value of tallying these emissions in the fight to prevent future oil projects. Plus, why Native American protesters and their allies deserve credit for keeping fossil fuels in the ground—and the bigger environmental justice issue of pipeline projects alongside Native land.

Native Biodata, Indigenous Carbon Resistance, COVID Boosters Next Steps. Oct 15, 2021, Part 1

The Hot And Cold Past Of The Air Conditioner In the Northeast, the leaves have started changing colors, heralding the season of pumpkins, sweaters, and the smell of woodsmoke. But in some parts of the country, the heat hasn’t let up. In cities like Dallas, Phoenix, and Miami, temperatures were up in the high 80s and low 90s this week—and with climate change, the U.S. is only getting hotter.  But humans have come up with an ingenious way to keep the heat at bay: air conditioning. Widely considered one of the greatest engineering achievements of the 20th century, the technology has transformed how and where people live—and it’s prevented countless deaths. But it comes at a cost, and if we’re going to keep up with a warming climate, we’re going to need some other tricks to stay cool.  Like what you hear? Dive deeper with some of the sources we turned to while reporting.      See A Familiar Face? Thank These Brain Cells What happens when you see a familiar face? Light reflected from the face enters your eye, is focused onto the retina, and a signal travels up your optic nerve. But what exactly goes on in your brain after that is still somewhat mysterious.   Recently, researchers reported in the journal Science that they had identified a group of brain cells that seem tuned to respond only to familiar faces. The theory is that the specificity of those neurons helps to speed up processing of potentially important visual information. The work was done in monkeys, but the researchers are currently trying to identify similar brain structures in people.   Sofia Landi and Winrich Freiwald, two of the authors of the report, join Ira to talk about the research, and what it may tell us about how the brain and memory are organized. 

Air Conditioning, Face Recognition Neurons. Oct 8, 2021, Part 2

First Malaria Vaccine Is Approved by WHO The malaria parasite is one of the world’s deadliest infectious diseases, killing on average about 500,000 people per year—half of them children under the age of 5, nearly all of them in sub-Saharan Africa. Now, the World Health Organization has finally approved RTS,S or Mosquirix, the first vaccine against Plasmodium falciparum, which is the most deadly strain of the parasite. The vaccine has already been administered via a pilot program to 800,000 children in Kenya, Ghana, and Malawi, and in clinical trials showed an efficacy rate of about 50% against severe disease. WNYC’s Nsikan Akpan explains this and other stories, including a climate change-linked Nobel Prize in physics, controversy over the naming of the James Webb Space Telescope, and a new surveillance method that uses only the shadows you cast on a blank wall. Will Improved Testing And New Antivirals Change The Pandemic’s Path? Late last week, the pharmaceutical company Merck released data on a new antiviral medication called molnupiravir—a drug taken as a course of pills over five days that the company said was dramatically effective at keeping people with COVID-19 out of the hospital. In a press release, the company said that trial participants on the medication had a 50% lower risk of hospitalization or death compared to people getting the placebo. And while eight people in the placebo group died during the trial, none of the people getting the new drug did. However, the full data from the trial has yet to be released—and the medication must still go through the FDA approval process before it can be used. Matthew Herper, senior writer at STAT covering medicine, joins Ira to talk about the drug and what questions remain. Then, infectious disease specialist and epidemiologist Céline Gounder discusses other recent coronavirus news—from a government plan to spend a billion dollars on at-home testing to recent data on the Delta variant, including projections of what might happen next. Preparing For The Next Pandemic Needs To Start Now The United States has a long history of public health crises. For many, our first pandemic has been COVID-19. But long before the SARS-CoV-2 virus arrived, HIV, measles, and the flu all left a lasting impact. As a wealthy country, you may think the United States would be prepared to deal with public health crises, since they happen here with a degree of regularity. However, that’s not the case. The longstanding issues that left the country vulnerable to COVID-19 are explored in a recent article from The Atlantic, called “We’re Already Barreling Toward the Next Pandemic.” The piece was written by science writer Ed Yong, who won a Pulitzer Prize last year for his coverage of COVID-19. Ira speaks to Ed and Gregg Gonsalves, global health activist and epidemiologist at Yale, about the country’s history of public health unpreparedness, and what needs to happen to be ready for the next pandemic.  

State Of COVID And Antiviral Pill, Future Pandemics. Oct 8, 2021, Part 1

Looking Back On A Century of Science In 1921, the discovery of radium was just over 20 years in the past. And the double helix of DNA was still over thirty years in the future. That year, a publication that came to be the magazine Science News started publication, and is still in operation today. Editors Nancy Shute and Elizabeth Quill join Ira to page through the magazine’s archives, with over 80,000 articles covering a century of science—from the possibilities of atomic energy to discussions of black holes, to projections of the rise of the avocado as a popular fruit. There are mysteries—are spiral nebulae other universes? And there are missteps, like the suggestion that the insecticide DDT should be incorporated into wall paint.     When The Water Comes The Science Friday Book Club is kicking off for fall. Producer Christie Taylor joins in a conversation with Elizabeth Rush, author of Rising: Dispatches from the New American Shore. They talk about the surprisingly fascinating science of coastal wetlands, and their role in protecting communities from sea level rise—plus how communities themselves, from Staten Island to southern Louisiana, are responding to rising seas and flooding. For the full rundown, excerpts, and more, check out our main Book Club page.   Who Will Sweep The Charismatic Creature Carnival? Our Charismatic Creature Carnival is coming to a close. Over the last month, SciFri has celebrated six overlooked or unfairly maligned species that deserve a chance under the spotlight. And now, out of our three semifinalist creature candidates, there can only be one winner. Will it be the colorful, tiny, but mighty mantis shrimp? Or perhaps the adaptable, dramatic opossum? Or will the endangered shoebill stork, with its prehistoric look, come out on top? The choice is up to our listeners: vote here.  

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