Featuring articles on a randomized trial of a pan-PPAR agonist in NASH, outcomes in nonalcoholic fatty liver disease, the AQP1 promoter variant and peritoneal dialysis, obesity in childhood and GNAS mutations, and optogenetics recognized through the Lasker Award; a review article on point-of-care ultrasonography; a case report of a girl with swelling of the jaw and hypercalcemia; and Perspective articles on blood donation by gay and bisexual men, on the case for wage equity for essential health care workers, and on peak moments. 

NEJM This Week - Audio Summaries

NEJM This Week — October 21, 2021

Featuring articles on empagliflozin in heart failure with preserved ejection fraction, oxytocin in autism spectrum disorder, breakthrough Covid-19 in health care workers, a cell-culture influenza vaccine, and data in crisis; a review article on aspergillus infections; a case report of a man with sore throat, epistaxis, and oropharyngeal petechiae; and Perspective articles on vigilante injustice, eviction and the necessary conditions for health, the drug-dosing conundrum in oncology, and on a good death. 

NEJM This Week — October 14, 2021

Featuring articles on Covid-19 vaccine effectiveness in medical settings, immediate vs. delayed drainage for infected necrotizing pancreatitis, bamlanivimab plus etesevimab for Covid-19, third dose of Covid-19 vaccine in Israel, broadly neutralizing antibodies against all coronaviruses, striving for diversity in research studies, and mRNA vaccine research and the Lasker–DeBakey Award; a review article on autoimmune hemolytic anemias; a Clinical Problem-Solving on a woman with throat pain; and Perspective articles on methods of public health research, on the No Surprises Act and informed financial consent, and on integrating research into community practice. 

NEJM This Week — October 7, 2021

Featuring articles on antidepressants in primary care practice, intensive blood-pressure control in older patients, ozanimod for ulcerative colitis, and Wnt proteins and structural birth defects; a review article on newer biologic and small-molecule therapies for IBD; a case report of a man with recurrent head and neck pain; and Perspective articles on moving toward a new era for the Indian Health System, on marking the 40th anniversary of the AIDS epidemic, and on cool water. 

NEJM This Week — September 30, 2021

Featuring articles on artemisinin-resistant malaria in Africa, safety and efficacy of the NVX-CoV2373 vaccine, subcutaneous antibody combination and Covid-19, tebentafusp for uveal melanoma, reenergizing HCV vaccine development, and HER2-mutated breast cancer and overcoming drug resistance; a review article on mesothelioma; a case report of a boy with fever and developmental regression; and Perspective articles on public health law after Covid-19 and on revitalizing the U.S. primary care infrastructure. 

NEJM This Week — September 23, 2021

Featuring articles on salt substitution and cardiovascular events, safety of the BNT162b2 mRNA Covid-19 vaccine, lutetium-177 in prostate cancer, typhoid vaccine in Malawian children, and a call for emergency action on the climate crisis; a review article on the treatment of acute appendicitis; a case report of a woman with Covid-19 and suicidal ideation; and Perspective articles on public option plans and on the treatment of older adults with cancer. 

NEJM This Week — September 16, 2021

Featuring articles on a trial of mobile stroke units, iron interventions in infants in rural Bangladesh, somatic mutations in sporadic cerebral cavernous malformations, malaria vaccination with or without chemoprevention, and sensible but very cool advances in protein chemistry; a review article on the challenges of sarcoidosis and its management; a case report of an adolescent seeking HIV prophylaxis; and Perspective articles on SARS-CoV-2 human challenge studies, on supporting value-based health care, and on environmental racism and climate change. 

NEJM This Week — September 9, 2021

Featuring articles on the inactivated SARS-CoV-2 vaccine in Chile, mycophenolate mofetil for immune thrombocytopenia, cardiovascular and renal outcomes with efpeglenatide, MRI-directed prostate biopsies, and natural killer cells in defense against HPV; a review article on chronic meningitis; a Clinical Problem-Solving describing inadequate support; and Perspective articles on population health and human rights, on Covid-induced changes in health care delivery, and on paying for digital health care. 

NEJM This Week — September 2, 2021

Featuring articles on therapeutic anticoagulation in hospitalized patients with Covid-19, anticoagulation in moderate Covid-19, a monoclonal antibody for malaria prevention, triple therapy for cystic fibrosis, modeling heart development, and remembering past lessons about structural racism; a review article on heparin resistance; a case report of a man with relapsed acute myeloid leukemia; and Perspective articles on revisiting the FDA approval of aducanumab, on controversy and progress in Alzheimer’s disease, and on a pink salwar. 

NEJM This Week — August 26, 2021

Featuring articles on adjuvant pembrolizumab in renal-cell carcinoma, oral atogepant for migraine prevention, male infertility and small noncoding RNAs, and adjunct immune globulin for vaccine-induced thrombotic thrombocytopenia; a review article on long-term survival after kidney transplantation; a case report of a man with fatigue and leg swelling; and Perspective articles on ending the campaign to undo the ACA in the courts, on Medicare Physician Payment Reform, and on the Covid-19 infodemic. 

NEJM This Week — August 19, 2021

Featuring articles on vaccine effectiveness against the delta Covid-19 variant, injectable cabotegravir for prevention of HIV infection, antibody to factor XI after total knee replacement, year 1 of the Bundled Payments for Care Improvement–Advanced payment model, and on a new dimension in the RNA world; a review article on signature cytokines and immune-mediated inflammatory diseases; a case report of a woman with fever, sore throat, and confusion; and Perspective articles on confronting long-haul Covid, on the criminalization of gender-affirming care, and on when low tech wins. 

NEJM This Week — August 12, 2021

Featuring articles on CRISPR-Cas9 disruption of TTR in transthyretin amyloidosis, tirzepatide versus semaglutide for type 2 diabetes, milrinone or dobutamine for cardiogenic shock, decompression versus fusion for lumbar spondylolisthesis, and SARS-CoV-2 and immunosuppression; a review article on age-related macular degeneration; a Clinical Problem-Solving on turning purple with pain; and Perspective articles on the complementarity of public health and medicine, on contact tracing for Covid-19, on supporting trainees from groups that are underrepresented in medicine, and on establishing medical civil rights. 

NEJM This Week — August 5, 2021

We discuss the latest in medical research and ideas.

NEJM This Week — March 19, 2020

NEJM This Week — March 12, 2020

NEJM This Week — March 5, 2020

The New England Journal of Medicine (NEJM) Weekly Audio Summary RSS feed. NEJM (http://www.nejm.org) is a weekly general medical journal that publishes new medical research findings, review articles, and editorial opinion on a wide variety of topics of importance to biomedical science and clinical practice.

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NEJM This Week - Audio Summaries

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